Insulin resistance is when the process in your body that responds to glucose is no longer effective. The body has so many fascinating signals that occur for metabolic processes to engage. When we consume food, there are receptors in the gut (GLP-1 receptors) that trigger a response from the pancreas. The pancreas then sends insulin to the body to balance the glucose consumed. Overtime, this process becomes weak and inefficient requiring more insulin to be secreted to do the same work that less insulin could previously do. I like to think of this as an overworked, underpaid employee. If an employee is overworked and underpaid they may try and try to make things work and maintain balance. But, eventually they’re going to give up. The pancreas eventually becomes less and less effective on responding appropriately to the glucose. This leads to higher levels of circulating glucose and type 2 diabetes mellitus.
So, with the big talk of Semaglutide lately – how does it fit in the insulin resistance model? Semaglutide is a GLP-1 agonist. GLP stands for glucose like peptide. These medications (Semaglutide, Liraglutide, etc) work by signaling to the pancreas to release insulin in response to glucose. Basically they’re helping their worker-friend (pancreas) by giving a stronger signal then the body is doing alone (at the stage of insulin resistance). GLP-1s also help to curb the appetite. For most people, this is effective in reducing caloric intake.
Can you imagine the potential success of a metabolic-fixing medication (Semaglutide)??! With diet and exercise, the rate of success soars! If a medication can “fix” the underlying cause of your inability to lose weight then you’re more likely to have success!
Call today to discuss Medication Weight Loss treatments to find out what’s right for you! We off Semaglutide and MORE!